Platforms

Our human Trophoblast Stem Cell (hTSC) platform is a highly scalable, ethically sourced, and the youngest human stem cell platform that naturally performs prerequisite functions to affect many diseases

Starting Material Platforms

hTSC derived cell lines and exosomes are the best starting materials for regenerative medicine

hTSC
iPSC
Exosomes

hTSC

15 GMP-eligible cell lines and corresponding RUO cell lines that naturally express tens of thousands of markers for many genetic pathways

Advantages

  • Express thousands of markers for many genetic pathways 
  • Earliest ethically sourced pluripotent human stem cell
  • Immune privileged
  • Genetically stable
  • Freedom-to-operate globally

iPSC

Reprogramed from hTSC, the earliest starting material of any commercial iPSC

Advantages

  • Earliest ethically sourced starting material
  • Not attributed to a living donor
  • Genetically stable 
  • Intracellular HLA markers
  • Freedom-to-operate globally 
    (mRNA reprogramming, not subject to Yamanaka factors)
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ABX-005ABX-006

Exosomes

Produced by hTSC, the youngest ethically sourced human stem cell

Advantages

  • Produced by the earliest ethically sourced human stem cell
  • Inherits multi-functionality from hTSC
  • High purity exosomes
  • Standardized CMC, consistent exosomes
  • Freedom-to-operate globally
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ABX-004

Genetically Engineered Platforms

GEMS further expands the capabilities of our hTSC and iPSC platforms.  
It also has been integrated into a variety of other human and rodent cell types.

GEMS
CHO-GEMS

GEMS

Allows for precision complex genetic editing without random insertion for combination cell therapy, mAB, viral vector, and complex protein production

Advantages

  • Up to 10 engineered cutting sites
  • Easily integrated with any cell line with any editing methods
  • Proof of concept for many human and rodent cell types, donor genes ranging from CAR, to mAB, growth regulator, safety switches, etc.
  • Allows for insertion and removal of genes
Learn more on how to build GEMS enabled cell lines, the future for precision medicine
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CHO-GEMS

Pre-engineered antibody production platform designed for complex, multi-specific antibodies

Advantages

  • Pre-designed cutting sites for rapid prototyping of antibody design to ensure the highest efficiency and production
  • Pre-integrated with leading CDMOs to allow for a cost-effective and fast-paced transition from research to commercialization
  • Experienced cell-line development specialists to help you every step of the way to commercialize your complex antibody product
Learn more about our CHO-GEMS cell lines 
Contact for Information

Connect with us to learn more about our hTSC and derived platforms

We are ready to share our hTSCs with you to help you accelerate your research and product development.

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